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The much-anticipated 22nd season of Grey's Anatomy is just around the corner, set to air on ABC and Disney Plus.

In a shocking twist at the end of the previous season, Grey Sloan Memorial Hospital was caught in a potentially deadly explosion, leaving fans anxious about the fate of their favourite characters.

Showrunner Meg Marinis confessed that there were some disputes regarding the aftermath of the explosion.

"I knew what I thought initially [about the outcome of the explosion], but I wanted to wait until my writers were back, so that people could also fight and argue with me.

"And so some things changed, some didn't [in regards to how it pans out]. But I want to give everyone a chance to fight for what happens to specific characters," she disclosed to Entertainment Weekly.

Here's everything you need to know about the upcoming season, including the release date, cast, and more.

The 22nd season of Grey's Anatomy will premiere in the US on 9 October at 10/9c on ABC, and will be available to stream on Hulu the following day.

Internationally, including in the UK, the new series will be available from 10 October on Disney Plus.

The season comprises 18 episodes in total, which will continue to air weekly.

Ellen Pompeo will reprise her role as Meredith Grey, alongside main cast members Chandra Wilson as Miranda Bailey, James Pickens Jr as Dr Richard Webber, and Kevin McKidd as Dr Owen Hunt.

Also returning are Caterina Scorsone as Amelia Shepherd, Camilla Luddington as Jo Wilson, and Jason George as Ben Warren.

The remaining principal cast members are as follows:

Kim Raver portraying Teddy Altman

Chris Carmack portraying Atticus "Link" Lincoln

Anthony Hill portraying Winston Ndugu

Alexis Floyd portraying Simone Griffith

Harry Shum Jr. portraying Benson "Blue" Kwan

Adelaide Kane portraying Jules Millin

Niko Terho portraying Lucas Adams

Marinis hinted that viewers can expect significantly more screen time for Trevor Jackson, who takes on the role of Simone's fresh-faced intern.

"He's so talented. It's been so fun with him on set already, and he is definitely mixing up the dynamics between our resident cast members, specifically Simone and Lucas," she revealed.

Indeed, ABC unveiled the complete trailer at the beginning of October, depicting the horrifying consequences of the explosion, with apparently motionless figures scattered across the ground.

Concerns emerge regarding potential deaths and the scale of devastation, though specific details remain under wraps for now.

Meredith appears visibly devastated as she attempts to comprehend the carnage surrounding her.

Grey's Anatomy season 22 will premiere in the US on October 9 on ABC. It will air in the UK and internationally from October 10 on Disney Plus.

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